Anton J M de Craen Selected Research

Pravastatin (Pravachol)

1/2017	Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients.
1/2016	Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study.
9/2015	Executive function, but not memory, associates with incident coronary heart disease and stroke.
7/2015	Infratentorial Microbleeds: Another Sign of Microangiopathy in Migraine.
7/2014	In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.
7/2014	ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment.
2/2014	Homocysteine levels and treatment effect in the PROspective Study of Pravastatin in the Elderly at Risk.
1/2013	Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).
1/2013	Subclinical thyroid dysfunction and cognitive decline in old age.
2/2012	KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

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Anton J M de Craen Research Topics

Disease

26	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 06/2002
23	Cognitive Dysfunction 02/2017 - 06/2002
17	Stroke (Strokes) 02/2017 - 06/2002
12	Inflammation (Inflammations) 11/2018 - 05/2007
12	Dementia (Dementias) 02/2017 - 06/2002
12	Vascular Diseases (Vascular Disease) 01/2017 - 08/2005
12	Neoplasms (Cancer) 07/2014 - 01/2005
10	Breast Neoplasms (Breast Cancer) 04/2016 - 01/2011
10	Coronary Disease (Coronary Heart Disease) 02/2014 - 01/2008
8	Myocardial Infarction 01/2017 - 01/2008
8	Hypertension (High Blood Pressure) 01/2016 - 11/2008
6	Type 2 Diabetes Mellitus (MODY) 01/2017 - 04/2002
6	Diabetes Mellitus 06/2015 - 01/2009
4	Heart Failure 09/2014 - 12/2010
4	Heart Diseases (Heart Disease) 07/2014 - 05/2010
4	Infections 07/2013 - 02/2008
4	Anemia 03/2013 - 08/2009
3	Obesity 01/2017 - 09/2010
3	Hypothyroidism 01/2016 - 01/2013
3	Insulin Resistance 12/2014 - 07/2009
3	Osteoarthritis 09/2014 - 05/2005
2	Hearing Loss (Hearing Impairment) 01/2016 - 09/2012
2	Genetic Predisposition to Disease (Genetic Predisposition) 04/2015 - 05/2005
2	Neoplasm Metastasis (Metastasis) 04/2014 - 12/2009
2	Colonic Neoplasms (Colon Cancer) 06/2013 - 12/2012
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2010 - 04/2002
2	Chronic Disease (Chronic Diseases) 10/2005 - 09/2004
1	Necrosis 01/2020
1	Chronic Renal Insufficiency 01/2019
1	Orthostatic Hypotension (Postural Hypotension) 03/2016
1	Hyperthyroidism 01/2016
1	Hemorrhage 01/2016
1	Tics (Tic) 01/2016
1	von Willebrand Diseases (von Willebrand's Disease) 01/2016
1	Lupus Nephritis 01/2016
1	Migraine Disorders (Migraine) 07/2015
1	Epilepsy (Aura) 07/2015
1	Genetic Risk Score 04/2015
1	Body Weight (Weight, Body) 12/2014
1	Atrial Fibrillation 06/2014

Drug/Important Bio-Agent (IBA)

23	Pravastatin (Pravachol)FDA LinkGeneric 01/2017 - 08/2005
13	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 01/2008
12	C-Reactive ProteinIBA 11/2018 - 01/2009
9	Biomarkers (Surrogate Marker)IBA 11/2018 - 01/2009
9	Glucose (Dextrose)FDA LinkGeneric 04/2015 - 04/2002
8	CytokinesIBA 01/2020 - 04/2002
8	HDL CholesterolIBA 12/2014 - 06/2002
7	HomocysteineIBA 02/2017 - 10/2005
7	LipidsIBA 01/2017 - 04/2002
7	Hormones (Hormone)IBA 01/2016 - 01/2012
7	oxidized low density lipoproteinIBA 04/2015 - 09/2008
6	Interleukin-10 (Interleukin 10)IBA 01/2020 - 04/2002
6	Antihypertensive Agents (Antihypertensives)IBA 03/2016 - 02/2008
6	LDL CholesterolIBA 07/2014 - 09/2008
6	ApolipoproteinsIBA 01/2013 - 04/2007
6	Apolipoproteins E (ApoE)IBA 09/2012 - 06/2006
6	CholesterolIBA 09/2010 - 06/2002
5	pro-brain natriuretic peptide (1-76)IBA 09/2014 - 01/2013
4	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020 - 09/2004
4	Interleukin-6 (Interleukin 6)IBA 02/2017 - 09/2004
4	Folic Acid (Vitamin M)FDA LinkGeneric 07/2012 - 10/2005
4	LDL Lipoproteins (beta Lipoproteins)IBA 02/2012 - 09/2008
3	InterleukinsIBA 01/2020 - 06/2009
3	Thyroid HormonesIBA 01/2019 - 02/2012
3	exemestane (Aromasin)FDA Link 01/2016 - 01/2013
3	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2016 - 12/2004
3	Tamoxifen FDA LinkGeneric 01/2016 - 01/2013
3	Pharmaceutical PreparationsIBA 01/2015 - 01/2005
3	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2014 - 01/2013
3	Insulin (Novolin)FDA Link 01/2011 - 07/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2010 - 09/2004
3	HDL LipoproteinsIBA 01/2009 - 06/2002
2	Biological ProductsIBA 01/2017 - 04/2015
2	von Willebrand FactorIBA 01/2016 - 02/2014
2	LeptinIBA 09/2014 - 02/2009
2	Hemoglobins (Hemoglobin)IBA 03/2013 - 05/2010
2	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2013 - 12/2004
2	Vitamin B Complex (B Vitamins)IBA 03/2011 - 07/2006
2	CreatinineIBA 03/2011 - 08/2009
2	Lipoproteins (Lipoprotein)IBA 05/2010 - 04/2002
2	Apolipoprotein E2IBA 12/2009 - 04/2007
1	InterferonsIBA 01/2020
1	Interleukin-12 (IL 12)IBA 01/2020
1	omega-Chloroacetophenone (Mace)IBA 01/2017
1	Natriuretic PeptidesIBA 09/2016
1	Antidepressive Agents (Antidepressants)IBA 01/2016
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2016
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 06/2015
1	Glutamic Acid (Glutamate)FDA Link 02/2015
1	AdiponectinIBA 09/2014
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 07/2014
1	Formaldehyde (Formol)FDA Link 07/2014
1	Phenobarbital (Luminal)FDA Link 07/2014
1	ParaffinIBA 07/2014

Therapy/Procedure

14	Therapeutics 01/2017 - 01/2009
6	Activities of Daily Living (ADL) 06/2014 - 10/2005
2	Drug Therapy (Chemotherapy) 06/2013 - 01/2013
1	Secondary Prevention 01/2017
1	Bathroom Equipment 01/2016
1	Radiotherapy 03/2014